Calm and stress · 6 min read
The physiological sigh: two breaths in, one long breath out
You sigh every few minutes, mostly without noticing. The physiological sigh turns that reflex into a tiny exercise: two inhales through the nose, then one long exhale. You may have heard it called the fastest way to calm down. Here’s how to do it, what happens in your body and what the research actually shows.
Key takeaways
- How to do it: inhale through your nose, take a second short inhale on top, then breathe out slowly and completely, ideally through your mouth.
- In the moment, one to three sighs are enough. In the best-known study, people practiced for five minutes a day.
- The evidence: in a Stanford study of 108 healthy adults, daily cyclic sighing lifted mood a bit more than mindfulness meditation. Anxious feelings went down about equally in all groups.
- The long exhale matters: your heart beats slightly slower as you breathe out, and in lab tests, breathing out longer than in felt more relaxing.
- Fastest way to calm down? That hasn’t been tested. It has been compared with only a few other exercises, and box breathing often did about as well.
How to do a physiological sigh
- Sit or lie down comfortably and let your shoulders drop.
- Breathe in through your nose until your lungs feel full.
- Without breathing out, sneak in a second, shorter inhale through your nose. It’s smaller than the first one, and that’s how it should be.
- Breathe out slowly and all the way, through your mouth or your nose. The exhale takes clearly longer than both inhales together.
- One to three sighs are enough in the moment. Then go back to breathing normally.
That’s also how the Stanford researchers taught it: two inhales through the nose, a slow exhale through the mouth. People who preferred to breathe only through the nose were allowed to.1
Six sighs, one minute
Tap Breathe along when you’re ready
What happens in your body
Nobody invented sighing. Your body does it on its own: every few minutes, the breathing center in your brainstem slips in a deeper breath. These spontaneous sighs reinflate the alveoli, the tiny air sacs in your lungs. We sigh more under stress and when oxygen runs low.2 In mice, researchers have found the circuit behind it: about 200 nerve cells in the breathing rhythm generator that turn normal breaths into sighs.2
A sigh also seems to tidy up your breathing. In 42 healthy adults sitting quietly, breathing became more and more irregular before a spontaneous sigh and more orderly after it.3 The research team proposes that a sigh works like a reset button for both breathing and emotions, which is why it brings relief.4
- Calm breathing: small, even breaths.
- The first inhale through the nose, deeper than usual.
- A second, short inhale on top, until your lungs are completely full.
- A long, slow exhale until your lungs are back at rest.
- Your heart beats slightly faster as you breathe in and slightly slower as you breathe out. A long exhale gives the slower part more time.
The second half of the exercise is the long exhale. Your heart speeding up slightly as you breathe in and slowing slightly as you breathe out is completely normal. It’s called respiratory sinus arrhythmia.5 In a lab study with 30 adults, people felt more relaxed when they breathed out longer than they breathed in, regardless of whether they breathed fast or slow.6
You’ll often read that the double inhale pops open collapsed air sacs so you can offload more carbon dioxide. That’s a plausible idea, but it hasn’t been tested directly for the deliberate exercise. What’s been studied is the exercise as a whole, not that explanation.
What the Stanford study found, and what it didn’t
The best-known study comes from Stanford University and was published in 2023.1 108 healthy adults practiced for five minutes every day for a month. They were randomly assigned to one of four groups:
| Group | Exercise | People |
|---|---|---|
| Cyclic sighing | physiological sighs, five minutes in a row | 30 |
| Box breathing | in, hold, out, hold, all the same length | 21 |
| Fast breathing with holds | long inhales, short exhales, then a breath hold | 33 |
| Mindfulness meditation | for comparison: just observing the breath | 24 |
All four groups felt less anxious and less down after their daily session, and by similar amounts. For positive mood, the breathing exercises came out ahead. But only cyclic sighing beat meditation by a statistically clear margin, and its lead grew the more days people practiced. Cyclic sighing also lowered the breathing rate measured daily by a wrist tracker more than meditation did. Resting heart rate, heart rate variability and sleep didn’t change meaningfully in any group.1 The study tested the technique, not the nowa app.
The study has limits, and the researchers name them. It ran online, with nobody watching people practice. On average, participants practiced on just under 20 of 28 days. It was designed as a pilot for a larger trial, and each group was small. People with heart disease, seizures, glaucoma, pregnancy or certain mental health conditions weren’t included.1
What newer research adds
Since 2025, two smaller studies have tested the sigh in real-world settings:
- In tense everyday moments: 47 students did one minute of cyclic sighing, one minute of box breathing, or nothing when they felt tense. Both breathing exercises lowered in-the-moment anxious feelings more than doing nothing. Reaction times on an attention test were a bit slower afterward, though.7
- After an all-out workout: in 62 military cadets, the calming branch of the nervous system bounced back faster with sighing or box breathing than with normal breathing, measured by heart rate variability. Heart rate dropped about equally fast in all groups.8
Both are small studies. They point in the same direction but don’t prove that the sigh beats other slow breathing exercises. In both, box breathing did about as well.
Is it really the fastest way to calm down?
That claim goes further than the evidence. The studies above compare the sigh with a handful of other exercises, not with every way people calm down, and box breathing often kept up. What the research does support is more modest: a meta-analysis of 12 randomized trials with 785 adults found that breathing exercises lower stress by a small to moderate amount on average, and its authors explicitly warn against letting hype run ahead of the evidence.9
The physiological sigh isn’t magic. It’s one of the few breathing exercises tested head to head in randomized trials, it takes ten seconds, and it costs nothing.
When it fits, and when something else might be better
The sigh is short and easy to hide. It fits the moments when things get tight: before a hard conversation, after a scare, when your head is too full, while you’re stuck in traffic or in line. You can do it sitting, lying down or standing.
For a longer break or for bedtime, exercises that slow your breathing down over several minutes are often a better fit, such as coherent breathing or these breathing exercises for sleep.
If you have panic attacks or an anxiety disorder: breathing exercises don’t replace treatment. Talk with your doctor or therapist about whether, and which, exercises suit you.
Common mistakes
- Too many sighs, too fast. If you feel dizzy or notice tingling in your hands or lips, you’re probably breathing too much. Exhale slowly, take a break after a few sighs and breathe normally.
- Breathing out between the two inhales. The second inhale goes on top, with no pause and no exhale in between.
- Lifting your shoulders. Let the breath go into your belly and sides, and keep your shoulders down.
- Pushing the air out. Just let it flow out, like a sigh of relief.
Frequently asked questions
- How many physiological sighs should I do?
- One to three are enough in the moment. In the Stanford study, people did five minutes a day in a row. If you get dizzy, you’re doing too many too quickly.
- Should I breathe through my nose or my mouth?
- In through the nose and out through the mouth, as in the study. Nose only works, too.1
- Physiological sigh or box breathing?
- Both did well in the studies so far. The sigh is quicker and easier to do on the spot, while box breathing has more structure and holds. Try both and keep the one that feels better. Box breathing is free in nowa, too.
- Is a physiological sigh the same as cyclic sighing?
- Almost. A physiological sigh is a single double inhale with a long exhale. Cyclic sighing means repeating it for several minutes, as in the studies.
- Does it help you fall asleep?
- That hasn’t been tested directly. In the Stanford study, the sleep data from the wrist tracker didn’t change in any group.1 For falling asleep, slow exercises over several minutes are a more natural fit.
This article shares general information about breathing exercises for relaxation and well-being. It is not medical advice and does not replace diagnosis or treatment by a licensed professional. nowa is a wellness app. It is not a medical device and is not intended to diagnose, treat, cure, or prevent any disease. Only practice while it feels comfortable. If you feel dizzy or short of breath, or notice a racing heart, chest pain, or strong anxiety, stop and breathe normally. If you have a medical condition (for example a heart or lung condition, or epilepsy) or are pregnant, talk to your doctor or midwife before trying new breathing exercises. Never change prescribed treatment on your own.
Sources
- Balban MY, Neri E, Kogon MM, Weed L, Nouriani B, Jo B, Holl G, Zeitzer JM, Spiegel D, Huberman AD (2023). Brief structured respiration practices enhance mood and reduce physiological arousal. Cell Reports Medicine 4(1):100895. doi.org/10.1016/j.xcrm.2022.100895
Randomized controlled trial, online, 108 adults, one month - Li P, Janczewski WA, Yackle K, Kam K, Pagliardini S, Krasnow MA, Feldman JL (2016). The peptidergic control circuit for sighing. Nature 530:293–297. doi.org/10.1038/nature16964
Basic research in mice - Vlemincx E, Van Diest I, Lehrer PM, Aubert AE, Van den Bergh O (2010). Respiratory variability preceding and following sighs: a resetter hypothesis. Biological Psychology 84(1):82–87. doi.org/10.1016/j.biopsycho.2009.09.002
Measurements in 42 healthy adults - Vlemincx E, Abelson JL, Lehrer PM, Davenport PW, Van Diest I, Van den Bergh O (2013). Respiratory variability and sighing: a psychophysiological reset model. Biological Psychology 93(1):24–32. doi.org/10.1016/j.biopsycho.2012.12.001
Review - Yasuma F, Hayano J (2004). Respiratory sinus arrhythmia: why does the heartbeat synchronize with respiratory rhythm? Chest 125(2):683–690. doi.org/10.1378/chest.125.2.683
Review - Van Diest I, Verstappen K, Aubert AE, Widjaja D, Vansteenwegen D, Vlemincx E (2014). Inhalation/exhalation ratio modulates the effect of slow breathing on heart rate variability and relaxation. Applied Psychophysiology and Biofeedback 39(3–4):171–180. doi.org/10.1007/s10484-014-9253-x
Lab study, 30 adults - Riedl EM, Bracklo T, Wimmer K, Perzl J, Gdynia HJ, Thomas J, Surzykiewicz J (2026). Simply breathing anxiety away? A pilot, just-in-time ecological momentary intervention study of one-minute cyclic sighing versus box breathing as tools for acute anxiety reduction and attention promotion in real life. Anxiety, Stress, & Coping 39(5):608–622. doi.org/10.1080/10615806.2026.2659809
Preregistered real-life pilot study, 47 students - Jones ME, Smith G, Acevedo A, Melton B (2026). Effectiveness of structured breathwork interventions on heart rate variability and heart rate recovery following maximal exertion in tactical athletes. Medicine & Science in Sports & Exercise 58(7):1524–1533. doi.org/10.1249/MSS.0000000000003972
Randomized controlled trial, 62 cadets - Fincham GW, Strauss C, Montero-Marin J, Cavanagh K (2023). Effect of breathwork on stress and mental health: a meta-analysis of randomised-controlled trials. Scientific Reports 13:432. doi.org/10.1038/s41598-022-27247-y
Meta-analysis, 12 randomized trials on stress with 785 adults
All sources last checked on October 28, 2026. Spotted a mistake? Write to support@nowabreathing.com and I’ll fix it and note the change here.